Technology Platforms
Biologics Drug Discovery
Dotquant is developing advanced biologics based on DNA and RNA for targeted therapy and drug delivery. The outstanding specificity of oligonucleotide base-paring and the high degree of flexibility of post-production modifications enable a host of solutions to immunotherapy and anti-sense therapy. In addition to our own drug pipelines, Dotquant also provides aptamer screening services. Details can be found here.
Custom RNA Synthesis
Although we focus on drug discovery and development, we also make our propitiatory in vitro transcription technology available to the broader scientific communities including ncRNAs, aptamers, aptamer-siRNA chimeras, aptamer-microRNA chimeras, CRISPR guides, ribozymes, and microRNAs, where long chemically modified RNAs are needed. We custom synthesize 2’F-modified RNAs of medium to long lengths (60-400 NTs) at affordable prices.
Advanced Imaging Technology
In alignment with our mission to enhance disease diagnosis and enable the development of companion diagnostics, we also advances cutting-edge imaging technologies, integrating imaging probes, instrumentation, and optimized imaging protocols.