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Technology Platforms

Biologics Drug Discovery

Dotquant is developing advanced biologics based on DNA and RNA for targeted therapy and drug delivery. The outstanding specificity of oligonucleotide base-paring and the high degree of flexibility of post-production modifications enable a host of solutions to immunotherapy and anti-sense therapy. In addition to our own drug pipelines, Dotquant also provides aptamer screening services. Details can be found here.

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Custom RNA Synthesis

Although we focus on drug discovery and development, we also make our propitiatory in vitro transcription technology available to the broader scientific communities including ncRNAs, aptamers, aptamer-siRNA chimeras, aptamer-microRNA chimeras, CRISPR guides, ribozymes, and microRNAs, where long chemically modified RNAs are needed. We custom synthesize 2’F-modified RNAs of medium to long lengths (60-400 NTs) at affordable prices.

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